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PICOCS INVESTMENT PROJECT
PROGRAM: “PICoCs” - Investment programs to fight Coronaviruses
Development Contract (Ministerial Decree of 09.12.2014)
Prot. CDS 000864
Beneficiaries:
  • IRBM S.p.A.
  • ADVAXIA Biologics S.r.l

The IRBM Group launches “PICoCs” (Investment Programs to fight Coronaviruses), a three-year investment program of 33 million euros, containing projects aimed at expanding the Group’s research and development activities in Pomezia (RM) for drugs and infrastructure.

The overall goal of the program is to give a synergistic response on several fronts to the fight against the Coronavirus family, through the strengthening of the IRBM and Advaxia Biologics companies, in terms of countering and treating other possible new infections that may occur in the coming years.

IRBM Investment Project
CUP C55H22000050001

The Project is made up by of two integrated but distinct lines of intervention:

New Laboratories Project – the project aims at expanding the research activities of all the main scientific units of IRBM in order to enhance the operational capacity of the laboratories and increase the range and quality of services offered on the market, includingthe introduction of cutting-edge scientific instrumentation.

The areas involved in the investment project include:

  1. DMPK
  2. High Throughput biology & Screening
  3. Display Technologies
  4. Medicinal Chemistry
  5. Peptide Chemistry
  6. High Content Biology & Screening
  7. Area New Biology

External Technical Unit Project: to support the New Laboratories Project, a new technical building will be built, with the aim of relocating and rationalizing activities currently distributed in the Main Building. The building will be a 2-story above-ground construction made of precast prestressed concrete structure, including infill paneling.

Financial support: Invitalia, the National Agency for Inward Investment and Economic Development (https://www.invitalia.it/eng) will support the Program through a “Contratto di Sviluppo” (Development Contract), a Grant for large investments, managed on behalf of the Ministry of Business and Made in Italy (https://www.mimit.gov.it/en/) .

PICOCS R&D PROJECTS
PROGRAM: “PICoCs” - Investment programs to fight Coronaviruses
Development Contract (Ministerial Decree of 09.12.2014)
Prot. CDS 000864
Beneficiaries:
  • IRBM S.p.A.
  • ADVAXIA Biologics S.r.l

The IRBM Group launches “PICoCs” (Investment Programs to fight Coronaviruses), a three-year investment program of 33 million euros, containing projects aimed at expanding the research and development activities of the Group.

The overall objective of the program is to give a synergistic response on multiple fronts to the fight against the Coronavirus family, through the strengthening of the IRBM and Advaxia Biologics companies, in terms of countering and treatment of other possible new infections that could occur in the coming years.

In particular, the Research Program aims at the identification and development of two independent therapeutic strategies to prevent future pandemic outbreaks caused by new Coronaviruses.

  • Industrial Research Project RI1 “Identification and development of pan inhibitors of the Coronavirus helicase enzyme”
    CUP C55I22000610001
    Beneficiary: IRBM
    The aim of this project is to identify small molecules that can inhibit the helicase enzyme of Coronaviruses and to validate these drug candidates in animal models.
  • Industrial Research Project RI2 “Pan-Coronavirus inhibitors of the discontinuous synthesis of RNA”
    CUP C55I22000620001
    Beneficiary: IRBM
    The aim of the SP2 project is the identification of small molecules that could interfere with the discontinuous synthesis of Coronavirus RNA and their validation in in vivo pre-clinical models.
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