Bio-Layer Interferometry (BLI) based biosensor technology is a powerful tool to measure molecular interactions in real time. Due to its great flexibility, it allows us to detect, quantify and determine the kinetics of biomolecule interactions even in different types of complex biological matrixes. At IRBM, we rely on BLI for antibody and small molecule screening when high throughput is needed. We consider it as a must-to-have tool in all antibody development campaigns for fast and reliable hit screening based on affinity and hit clustering based on epitope binning.
