Our passion for science drives innovation in…
Virtual screening
Our structure- and ligand-based virtual screening can optimize your workflow to maximize your project’s efficiency. Moreover, we provide an automated benchmark assessment to select the best structure-based docking procedures. Statistical and graphical analysis of your results is also available through our extended integration of commercial/open-source software.
NMR
NMR spectroscopy is a powerful tool in drug discovery. We utilize several 600 MHz Avance Bruker spectrometers to support your project with:
- Structural, purity and stability checks
- Aggregation state analysis
- Determination of macromolecule 3D structure
- Protein/ligand interaction studies
- Chemical shift mapping
- Saturation-transfer difference (STD)
- 2D or 3D triple-resonance NMR
Our NMR team has perfected the use of this technology across a range of applications. We can study the 3D structure of biomolecules ranging from small peptides to large proteins and protein complexes. Moreover, we use structure-activity relationship analysis and Fragment-Based Drug Discovery (FBDD) to identify and develop hits in the early phases of drug discovery.
