November 11th, 2022 Position: Legal Specialist – IRBM, Legal & Program Management Unit – Ref.…
March 30th, 2022
Jr. Research Scientist – IRBM, ADME/Pharmacology Unit – Ref. 173 B
IRBM is a drug discovery and development company with a track record of success in accelerating and executing the translation of novel discoveries into clinically relevant therapeutic modalities, including small molecules, peptides, and proteins. IRBM is headquartered in Pomezia (Rome), Italy and provides several integrated pre-clinical laboratory services across the entire drug discovery process, ranging from target validation to clinical candidate molecule selection. The company collaborates with several Pharmaceutical companies, Biotech’s as well as research institutes and non-profit foundations working in a range of disease indications. IRBM is committed to the discovery and development of novel therapeutic agents that can help fight and cure diseases.
The discovery absorption, distribution, metabolism, and excretion (ADME) group within the Experimental Pharmacology Department at is seeking a highly qualified multi-disciplinary team-oriented Scientist having cell biology experience with emphasis on in vitro ADME assays. In this role you will provide support for a diverse portfolio that includes small molecules, peptides, and proteins.
You will be responsible for running existing in vitro ADME assays to support pre-clinical project teams and will also be involved in the troubleshooting and development of new ADME cell-based assays. You will gain the ability to conduct cell culture experiments, and experience investigating the fate of molecules.
A good understanding of laboratory equipment, automation, and associated software is desirable. You must be able to demonstrate strong experimental and problem-solving skills, excellent collaboration, and communication skills (both written and oral English), and an eagerness to learn. Demonstration of meeting timelines and excellent time management is favoured. The ability to work in a team-based drug discovery/development environment is essential. Experience in stem cells culture and differentiation would be considered a plus.
BA/BS in Pharmaceutical Science, Molecular Biology, or a related discipline. 1+ years or an equivalent combination of education and experience.
Experience with in vitro ADME assays, involving use of established and novel sub-cellular and cell-based systems (e.g., microsomes, hepatocytes, cell lines, long term co-culture models) and analysis primarily through LC/MS detection is preferred.