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Conformational modulation mediated by polyglutamine expansion in CAG repeat expansion disease-associated proteins.

By Verani, Margherita; Bustamante, Maria; Martufi, Paola; Daldin, Manuel; Cariulo, Cristina; Azzollini, Lucia; Fodale, Valentina; Puglisi, Francesca; Weiss, Andreas; MacDonald, Douglas; et al From Biochemical and Biophysical Research Communications (2016), 478(2), 949-955. Language: English, Database: CAPLUS, DOI:10.1016/j.bbrc.2016.08.057 We have previously…

Discovery and Characterization of Novel Anti-schistosomal Properties of the Anti-anginal Drug, Perhexiline and Its Impact on Schistosoma mansoni Male and Female Reproductive Systems.

By Guidi Alessandra; Lalli Cristiana; Ruberti Giovina; Perlas Emerald; Bolasco Giulia; Nibbio Martina; Monteagudo Edith; Bresciani Alberto From PLoS neglected tropical diseases (2016), 10(8), e0004928, Language: English, Database: MEDLINE Schistosomiasis, one of the world's greatest human neglected tropical diseases, is…

Use of ‘dilute-and-shoot’ liquid chromatography-high resolution mass spectrometry in preclinical research: application to a DMPK study of perhexiline in mouse plasma.

By Esposito, Simone; Bracacel, Elena; Nibbio, Martina; Speziale, Roberto; Orsatti, Laura; Veneziano, Maria; Monteagudo, Edith; Bonelli, Fabio From Journal of Pharmaceutical and Biomedical Analysis (2016), 118, 70-80. Language: English, Database: CAPLUS, DOI:10.1016/j.jpba.2015.10.004 This work describes a simple, sensitive and rapid…




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