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Tandem mass spectrometry-based assay for heparan-N-sulphatase in paediatric CSF: A potential pharmacodynamic biomarker for mucopolysaccharidosis type IIIA therapy

Ultra-sensitive tandem mass spectrometry-based assay development and validation The article, "LC-MS/MS Assay for Heparan-N-Sulphatase in Pediatric CSF: A Potential Pharmacodynamic Biomarker for Mucopolysaccharidosis Type IIIA Therapy," published in Clinica Chimica Acta, covers the development, optimization, and qualification of a highly…

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