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Our team’s outstanding medicinal chemistry skills and experience across all phases of drug discovery underpin everything we do and ensure we provide ‘fit-for-purpose’ solutions to your chemistry challenges. IRBM’s chemists have a proven track record in identifying, synthesising and advancing small molecule drug candidates that progress into the clinic. Streamlined workflows ensure we deliver world-class results in the shortest possible timeframes.

IRBM’s scientists, with experience acquired in global Pharma and CRO settings, will design cost-effective synthetic strategies and apply the best chemistry to produce any type of molecule. The unique mix of synthetic and analytic capabilities, compound libraries and hands-on experience provide the creative design environment needed to generate leads and go on to secure IP for your project.

We are proud of our track record in solving synthetic problems. Projects range from developing deuterated steroids to complex macrocycles, from nucleoside analogs to challenging heterocycles, from sugars to peptidomimetics and from PROTACs to molecular glues.

OUR CAPABILITIES INCLUDE:

State-of-the-art organic and analytic chemistry facilities, with photochemistry and electrochemistry approaches as standard

  • Centralized automated compound purification and analysis
  • Scale-up chemistry up to 20L reaction volumes for research
    intermediates and non-GLP API
  • Research scale chiral separations by SFC
  • synthesis technologies and robotic liquid/reagent handling

MEDICINAL
CHEMISTRY

SYNTHETIC
CHEMISTRY

COMPUTATIONAL
CHEMISTRY

COMPOUND
MANAGEMENT

COMPOUND
LIBRARIES

We work with a range of clients in big pharma, biotech start-ups and
with organisations in the charity sector to deliver successful drug
discovery programs.

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