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IRBM is strongly tied to the idea that our chemists’ time should be dedicated to doing chemistry that brings value to the projects of our clients. Therefore, the logistics processes behind the purification, registration, and distribution of our compounds are centralized into a dedicated, skilled compound management team.

Our purification team supports our chemists with efficient, automated or manually tailored purification of final compounds and key intermediates. They employ an impressive instrumentation suite that includes the following:

STATE-OF-THE-ART INSTRUMENTATION SUITE

  • 2 Preparative scale Waters Automated HPLC (Fraction-Lynx with QDA-mass and SQD2-mass)
  • Preparative scale Waters HPLC (Mass Lynx) systems
  • Semi-preparative scale Waters SFC instrument
  • Super critical CO2 based Waters Acquity UPC2
  • 5 Waters UPLC/MS/ELSD
  • Waters QC-UPLC with sample organizer
  • TECAN Fluent for liquid handling and process automation
  • 2 Genevac EZ-2 Plus Evaporating System

Rigorous quality control (QC) of structural integrity and composition of our compounds is of high priority. The team uses our platform of UPLC/ELSD/MS instruments in combination with our four NMRs. Chiral samples are analyzed on our UPC2 routinely equipped with 4 columns and purified by SFC. The software also integrates with our Oracle compound databases, allowing rapid access to spectra and QC results.

Our strong cheminformatics systems also ensure that all compound analyses, shipping requirements and registration details can be shared effectively, regardless of your organization’s location or IT infrastructure.

FIND OUT MORE ABOUT OUR CROSS FUNCTIONAL DRUG DISCOVERY SERVICES

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