Drug DiscoveryOctober 2024NeurodegenerationPeptidesPoster code 24013
About this poster
In this poster, we showcase an advanced peptide program designed to inhibit the MLH1-MSH3 interaction, a key target in the DNA Mismatch Repair pathway implicated in Huntington’s disease. We detail the development of biochemical and biophysical assays used to guide Structure-Activity Relationship (SAR) studies, resulting in increasingly potent peptide inhibitors.
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Identification of Peptides Targeting MLH1-MSH3 poster, code 24013
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