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Publications 2016

Vitamin B12 ameliorates the phenotype of a mouse model of DiGeorge syndrome.

Lania G, Bresciani A, Bisbocci M, Francone A, Colonna V, Altamura S, Baldini A. (2016)
Hum Mol Genet. 2016 Oct 15;25(20):4369-4375.

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Conformational modulation mediated by polyglutamine expansion in CAG repeat expansion disease-associated proteins.

Verani M, Bustamante M, Martufi P, Daldin M, Cariulo C, Azzollini L, Fodale V, Puglisi F, Weiss A, Macdonald D, Petricca L, Caricasole A. (2016)
Biochem Biophys Res Commun. 2016 Sep 16;478(2):949-55.

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Discovery and Characterization of Novel Anti-schistosomal Properties of the Anti-anginal Drug, Perhexiline and Its Impact on Schistosoma mansoni Male and Female Reproductive Systems.

Guidi A, Lalli C, Perlas E, Bolasco G, Nibbio M, Monteagudo E, Bresciani A, Ruberti G. (2016)
PLoS Negl Trop Dis. 2016 Aug 12;10(8):e0004928.

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Crosstalk between mismatch repair and base excision repair in human gastric cancer.

Simonelli V, Leuzzi G, Basile G, D’Errico M, Fortini P, Franchitto A, Viti V, Brown AR, Parlanti E, Pascucci B, Palli D, Giuliani A, Palombo F, Sobol RW, Dogliotti E. (2016)
Oncotarget. 2016 Jun 20;8(49):84827-84840.

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Discovery of a Selective Series of Inhibitors of Plasmodium falciparum HDACs.

Ontoria JM, Paonessa G, Ponzi S, Ferrigno F, Nizi E, Biancofiore I, Malancona S, Graziani R, Roberts D, Willis P, Bresciani A, Gennari N, Cecchetti O, Monteagudo E, Orsale MV, Veneziano M, Di Marco A, Cellucci A, Laufer R, Altamura S, Summa V, Harper S. (2016)
ACS Med Chem Lett. 2016 Mar 5;7(5):454-9.

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MK-4101, a Potent Inhibitor of the Hedgehog Pathway, Is Highly Active against Medulloblastoma and Basal Cell Carcinoma.

Filocamo G, Brunetti M, Colaceci F, Sasso R, Tanori M, Pasquali E, Alfonsi R, Mancuso M, Saran A, Lahm A, Di Marcotullio L, Steinkühler C, Pazzaglia S. (2016)
Mol Cancer Ther. 2016 Jun;15(6):1177-89.

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Use of ‘dilute-and-shoot’ liquid chromatography-high resolution mass spectrometry in preclinical research: application to a DMPK study of perhexiline in mouse plasma.

Esposito S, Bracacel E, Nibbio M, Speziale R, Orsatti L, Veneziano M, Monteagudo E, Bonelli F. (2016)
J Pharm Biomed Anal. 2016 Jan 25;118:70-80.

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