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Publications 2018

A liquid chromatography high-resolution mass spectrometry in vitro assay to assess metabolism at the injection site of subcutaneously administered therapeutic peptides.

Esposito S, de Leonibus ML, Ingenito R, Bianchi E, Orsatti L, Monteagudo E. (2018)
J Pharm Biomed Anal 2018 Jul 10; 159;449-458 [Epub ahead of print]

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Development of a Broadly Applicable Assay for Measurement of Glycan-Directed Enzymatic Activity.

Bresciani A, Cecchetti O, Missineo A, Pacifici PG, Tomei L, Rodems S. (2018)
SLAS Discov 2018 Jun 1: 2472555218782625. doi: 10.1177/2472555218782625 [Epub ahead of print]

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Early metabolic response to acute myocardial ischaemia in patients undergoing elective coronary angioplasty.

Di Marino S, Viceconte N, Lembo A, Summa V, Tanzilli G, Raparelli V, Truscelli G, Mangieri E, Gaudio C, Cicero DO. (2018)
Open Heart 2018 Mar 10;5(1): e000709

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Peptidomimetic nitrile inhibitors of malarial protease falcipain-2 with high selectivity against human cathepsins.

Nizi E, Sferrazza A, Fabbrini D, Nardi V, Andreini M, Graziani R, Gennari N, Bresciani A, Paonessa G, Harper S. (2018)
Bioorg Med Chem Lett 2018 May 15;28(9): 1540-1544.

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Quantifying autophagy using novel LC3B and p62 TR-FRET assays.

Bresciani A, Spiezia MC, Boggio R, Cariulo C, Nordheim A, Altobelli R, Kuhlbrodt K, Dominguez C, Munoz-Sanjuan I, Wityak J, Fodale V, Marchionini DM, Weiss A. (2018)
PLoS One 2018 Mar 19;13(3):e0194423

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Determination of acetyl coenzyme A in human whole blood by ultra-performance liquid chromatography-mass spectrometry.

Speziale R, Montesano C, De Leonibus ML, Bonelli F, Fezzardi P, Beconi MG, Monteagudo E, Elbaum D, Orsatti L. (2018)
J Chromatogr B Analyt Technol Biomed Life Sci 2018 April 15;1083:57-62

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Fosmetpantotenate (RE-024), a phosphopantothenate replacement therapy for pantothenate kinase-associated neurodegeneration:
Mechanism of action and efficacy in nonclinical models.

Elbaum D, Beconi MG, Monteagudo E, Di Marco A, Quinton MS, Lyons KA, Vaino A, Harper S. (2018)
PLoS One 2018 Mar 9;13(3):e0192028

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Polypharmacy through Phage Display: Selection of Glucagon and GLP-1 Receptor Co-agonists from a Phage-Displayed Peptide Library.

Demartis A, Lahm A, Tomei L, Beghetto E, Di Biasio V, Orvieto F, Frattolillo F, Carrington PE, Mumick S, Hawes B, Bianchi E, Palani A, Pessi A. (2018)
Sci Rep. 2018 Jan 12;8(1):585.

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