This month Genetic Engineering & Biotechnology News features IRBM in an article about ‘Image-based high-content screening and predictive cell-based assays for drug discovery and development.’
The article showcases our significant experience in implementing High-Content Screening, developing disease-relevant cellular models and combining the two approaches to support integrated drug discovery research plans.
We are delighted to publish our first paper of 2022 in the Journal of Pharmaceutical and Biomedical Analysis (Elsevier). Here we leveraged our peptide #ADME toolbox to gain a better understanding of the interplay between oligomerization, albumin binding and catabolism of lipidated peptides in the subcutaneous compartment, using #GLP-1 analogs as model peptides.
Following the first report in the Journal of Medicinal Chemistry in 2020, the IRBM peptide chemistry group is proud to announce a new publication on second generation, potent bi- and tricyclic PCSK9 inhibitor peptides in collaboration with the extraordinary drug discovery team at Merck & co.
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