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Discovery of a Novel Series of Imidazopyrazine Derivatives as Potent SHP2 Allosteric Inhibitors

Cover of ACS Medicinal Chemistry Letters, Volume 14, Issue 2 in which IRBM's work on SHP2 inhibitors in featured

By Esther Torrente, Valentina Fodale, Alina Ciammaichella, Federica Ferrigno, Jesus M. Ontoria, Simona Ponzi, Ilaria Rossetti, Alessio Sferrazza, Jérôme Amaudrut, Antonino Missineo, Simone Esposito, Simone Palombo, Martina Nibbio, Mauro Cerretani, Monica Bisbocci, Antonella Cellucci, Annalise di Marco, Cristina Alli, Vincenzo Pucci, Carlo Toniatti, and Alessia Petrocchi

ACS Medicinal Chemistry Letters 2023 14 (2), 156-162

DOI: 10.1021/acsmedchemlett.2c00454

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