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Regioselective synthesis of 7,8-dihydropyrrolo[1,2-a]pyrimidin-4(6H)-ones and 7,8-dihydropyrrolo[1,2-a]pyrimidin-2(6H)-ones

By Donghi, Monica; Pesci, Silvia; Summa, Vincenzo; Koch, Uwe; Spieser, Stephane; Gardelli, Cristina From Synlett (2010), (2), 235-239. Language: English, Database: CAPLUS, DOI:10.1055/s-0029-1218566 Annulated analogs e.g., I, II of 5,6-dihydroxypyrimidine-4-carboxylate ester and 5,6-dihydroxypyrimidine-4-carboxylamide were synthesized. The intermediary homoallylic amines were…

Coadministration of telomerase genetic vaccine and a novel TLR9 agonist in nonhuman primates. [Erratum to document cited in CA151:356283]

By Dharmapuri, Sridhar; Peruzzi, Daniela; Mennuni, Carmela; Calaruso, Francesco; Giampaoli, Saverio; Barbato, Gaetano; Kandimalla, Ekambar R.; Agrawal, Sudhir; Scarselli, Elis; Mesiti, Giuseppe; et al From Molecular Therapy (2010), 18(2), 447. Language: English, Database: CAPLUS, DOI:10.1038/mt.2009.276 The human telomerase reverse transcriptase…

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