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Discovery by organism based high-throughput screening of new multi-stage compounds affecting Schistosoma mansoni viability, egg formation and production.

By Guidi Alessandra; Lalli Cristiana; Gimmelli Roberto; Saccoccia Fulvio; Ruberti Giovina; Nizi Emanuela; Andreini Matteo; Harper Steven; Gennari Nadia; Bresciani Alberto From PLoS neglected tropical diseases (2017), 11(10), e0005994, Language: English, Database: MEDLINE Schistosomiasis, one of the most prevalent neglected…

Nuclear factor (erythroid-derived 2)-like 2 (NRF2) drug discovery: Biochemical toolbox to develop NRF2 activators by reversible binding of Kelch-like ECH-associated protein 1 (KEAP1).

By Bresciani, Alberto; Missineo, Antonino; Gallo, Mariana; Cerretani, Mauro; Fezzardi, Paola; Tomei, Licia; Cicero, Daniel Oscar; Altamura, Sergio; Santoprete, Alessia; Ingenito, Raffaele; et al From Archives of Biochemistry and Biophysics (2017), 631, 31-41. Language: English, Database: CAPLUS, DOI:10.1016/j.abb.2017.08.003 Mechanisms that…

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