BBB

Application of an in Vitro Blood−Brain Barrier Model in the Selection of Experimental Drug Candidates for the Treatment of Huntington’s Disease

By Di Marco, Annalise; Gonzalez Paz, Odalys; Fini, Ivan; Vignone, Domenico; Cellucci, Antonella; Battista, Maria Rosaria; Auciello, Giulio; Orsatti, Laura; Zini, Matteo; Monteagudo, Edith; et al From Molecular Pharmaceutics (2019), 16(5), 2069-2082. Language: English, Database: CAPLUS, DOI:10.1021/acs.molpharmaceut.9b00042 Investigating Blood-Brain Barrier…

IRBM’s publishes in Cells on establishing a human blood-brain barrier model for use in drug discovery for neurodegenerative diseases such as Huntington’s

The blood-brain barrier (BBB) is responsible for the homeostasis between the cerebral vasculature and the brain. It has a key role in regulating the influx and efflux of substances, in healthy and diseased states. Stem cell technology offers the opportunity to use human brain-specific cells to establish in vitro BBB models.

Back to news listing

IRBM IN THE NEWS

PRESS RELEASES

EVENTS

Back To Top
No results found...