Passionate about Science

World-class drug discovery expertise
and an unprecedented track record with 4 drugs on the market

Passionate about Science

World-class drug discovery expertise
and an unprecedented track record with 4 drugs on the market

IRBM to collaborate with MSD to develop peptides against coronavirus

Builds on Research to Combat Severe Acute Respiratory Syndrome (SARS)

21st July 2020, Rome, Italy – IRBM, a global Contract Research Organization today announced a new research collaboration agreement with MSD (tradename of Merck & Co., Inc., Kenilworth, NJ, USA) to identify and develop novel peptide therapeutics active against different strains of coronavirus, including SARS-CoV-2. The parties will collaborate in hit to lead optimization and preclinical drug development to rapidly advance selected candidates towards the clinic.

WHYUS

We offer a unique blend of broad scientific expertise, global pharma heritage, and unprecedented success in bringing drug discovery projects from conception to the clinic. With a passionate, interdisciplinary and accomplished team, and capabilities ranging from target validation to clinical candidate nomination, we bring great science to your project.

Publications

Track Record

Series of Novel and Highly Potent Cyclic Peptide PCSK9 Inhibitors Derived from an mRNA Display Screen and Optimized via Structure-Based Design

13 November 2020

Scientific Contributions

In the last few years macrocyclic peptides have emerged as a better class of lead candidates for inhibition of protein-protein interactions with respect to conventional small molecules. The IRBM peptide chemistry team collaborated with the teams at Merck & co. and RaPharma to develop potent macrocyclic peptide inhibitors of PCSK9 a key regulator of plasma LDL-cholesterol.

On July 7 University and Research Minister Gaetano Manfredi visited IRBM

3 September 2020

Events

“IRBM is an important Italian biotech centre , which is giving a strategic contribution to the development of one of the vaccines against Covid-19 , a very important reality from the scientific point of view at international level.

On June 18 Health Minister Roberto Speranza, together with Nicola Magrini Director General of AIFA, visited IRBM

3 September 2020

Events

"Only a safe, effective vaccine can take us out of the emergency. "We are proud of our scientists and of the excellence of Italian research" said minister Speranza.